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| Product name: | AF/LE Purified Anti-Human/Mouse/Rat CD47 Monoclonal Antibody |
| Catalog: | DL20293F |
| Synonyms : | Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP |
| Reactivity: | Human, Mouse, Rat |
| Applications: | FCM,WB,IH,IP,ICC&IF |
| Size: | 50 ug/500 ug/1 mg/ |
| Host: | Mouse |
| Clonality: | |
| Background: | CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRP??, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking. |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. |
| Dilution: | |
| Gene ID(Human): | 9,611,642,329,364 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |