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| Product name: | AF/LE Purified Anti-Rat CD8a Monoclonal Antibody |
| Catalog: | DL21152F |
| Synonyms : | T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL |
| Reactivity: | Rat |
| Applications: | FCM,Wb,IHC,IP |
| Size: | 50 ug/500 ug/1 mg/ |
| Host: | Mouse |
| Clonality: | |
| Background: | CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8??. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8?? chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 ???? heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck). |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. |
| Dilution: | |
| Gene ID(Human): | 24930 |
| Storage: | Store at 2~8℃. Do not freeze. |