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| Product name: | AF/LE Purified Anti-Mouse CD119 Monoclonal Antibody |
| Catalog: | DL21411F |
| Synonyms : | Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119 |
| Reactivity: | Mouse |
| Applications: | FCM |
| Size: | 50 ug/500 ug/1 mg/ |
| Host: | Rat |
| Clonality: | |
| Background: | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-??R?? chain. It is a class II cytokine receptor family member that serves as a IFN-??-binding chain associated with the IFN-?? ?? chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-?? induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-?? initiates and regulates a variety of immune responses. |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. |
| Dilution: | |
| Gene ID(Human): | 15979 |
| Storage: | Store at 2~8℃. Do not freeze. |