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| Product name: | Anti-Mouse CD54 Monoclonal Antibody(PE/Cyanine7 Conjugated) |
| Catalog: | DL20347F |
| Synonyms : | Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1 |
| Reactivity: | Mouse |
| Applications: | FCM |
| Size: | 50 Tests/100 Tests/200 Tests/500 Tests |
| Host: | Rat |
| Clonality: | |
| Background: | CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 15894 |
| Storage: | Store at 2~8℃. Do not freeze. |