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| Product name: | Anti-Mouse CD122 Monoclonal Antibody(FITC Conjugated) |
| Catalog: | DL20461F |
| Synonyms : | Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122 |
| Reactivity: | Mouse |
| Applications: | FCM |
| Size: | 50 Tests/100 Tests/500 Tests/ |
| Host: | Rat |
| Clonality: | |
| Background: | CD122 is a 70-75 kD IL-2 receptor ?? chain also known as IL-2R??, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2R?? chain can combine with either the common ?? subunit (??c, CD132) alone or with the ??c subunit and the IL-2R?? subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 16185 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |