地址:江苏省无锡市梁溪区锡沪东路8号301-2 电话:0510-82732223 / 86-0510-82732223 邮箱:info@dldevelop.com.cn
备案号:苏ICP备06050612号-1 苏公网安备 32020302000048号 版权所有 @2016 无锡市东林科技发展有限责任公司Language:English
Product name: | Anti-Mouse CD122 Monoclonal Antibody(AF488 Conjugated) |
Catalog: | DL20468F |
Synonyms : | Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122 |
Reactivity: | Mouse |
Applications: | FCM |
Size: | 20 Tests/50 Tests/100 Tests/500 Tests |
Host: | Rat |
Clonality: | |
Background: | CD122 is a 70-75 kD IL-2 receptor ?? chain also known as IL-2R??, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2R?? chain can combine with either the common ?? subunit (??c, CD132) alone or with the ??c subunit and the IL-2R?? subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
Concentration: | |
Immunogen: | |
Purification_Method: | |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Dilution: | |
Gene ID(Human): | 16185 |
Storage: | Store at 2~8℃. Do not freeze. |