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| Product name: | Anti-Human IL-21 Monoclonal Antibody(APC Conjugated) |
| Catalog: | DL22177F |
| Synonyms : | Interleukin-21,IL-21,Za11 |
| Reactivity: | Human |
| Applications: | ICFCM |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests |
| Host: | Mouse |
| Clonality: | |
| Background: | Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 59067 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |