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Product name: | AF/LE Purified Anti-Mouse CD132 Monoclonal Antibody |
Catalog: | DL20286F |
Synonyms : | Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132 |
Reactivity: | Mouse |
Applications: | FCM,IP |
Size: | 50 ug/500 ug/1 mg/ |
Host: | Rat |
Clonality: | |
Background: | CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common ?? chain (??c) or IL-2 receptor ?? subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID). |
Concentration: | 0.2 mg/mL |
Immunogen: | |
Purification_Method: | |
Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. |
Dilution: | |
Gene ID(Human): | 16186 |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |