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| Product name: | AF/LE Purified Anti-Mouse CD366/Tim-3 Monoclonal Antibody |
| Catalog: | DL22112F |
| Synonyms : | TIM3, TIMD3,HAVcr-2,TIMD-3 |
| Reactivity: | Mouse |
| Applications: | FCM,Block |
| Size: | 50 ug/500 ug/1 mg/ |
| Host: | Rat |
| Clonality: | |
| Background: | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. |
| Dilution: | |
| Gene ID(Human): | 84868 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |