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| Product name: | AF/LE Purified Anti-Human CD20 Monoclonal Antibody |
| Catalog: | DL22239F |
| Synonyms : | Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1 |
| Reactivity: | Human |
| Applications: | Depletion, FCM, IHC, IP |
| Size: | 50 ug/500 ug/1 mg/ |
| Host: | Mouse |
| Clonality: | |
| Background: | CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. |
| Dilution: | |
| Gene ID(Human): | 931 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |