地址：江苏省无锡市梁溪区锡沪东路8号301-2 电话：0510-82732223 / 86-0510-82732223 邮箱：info@dldevelop.com.cn
备案号：苏ICP备06050612号-1 苏公网安备 32020302000048号 版权所有 @2016 无锡市东林科技发展有限责任公司Language:English
电话:86-0510-82732223
邮箱:info@dldevelop.com.cn
| Product name: | Anti-Mouse CD103 Monoclonal Antibody(PE/Cyanine5 Conjugated) |
| Catalog: | DL21013F |
| Synonyms : | Integrin alpha-E,Itgae,Integrin alpha M290,CD103 |
| Reactivity: | Mouse |
| Applications: | FCM |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests |
| Host: | Rat |
| Clonality: | |
| Background: | CD103 is a type I transmembrane glycoprotein known as ??E integrin or Integrin ??IEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-?? stimulation. In association with integrin ??7, CD103 is expressed as ??E/??7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 16407 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |