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| Product name: | Anti-Human CD127/IL-7RA Monoclonal Antibody(AF647 Conjugated) |
| Catalog: | DL21823F |
| Synonyms : | Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7R?? |
| Reactivity: | Human |
| Applications: | FCM |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests |
| Host: | Mouse |
| Clonality: | |
| Background: | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor ?? chain or IL-7R??. It forms a heterodimer with the common ?? chain (??c or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 3575 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |