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| Product name: | Anti-Human CD161 Monoclonal Antibody(AF647 Conjugated) |
| Catalog: | DL21838F |
| Synonyms : | CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1 |
| Reactivity: | Human |
| Applications: | FCM |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests |
| Host: | Mouse |
| Clonality: | |
| Background: | CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 3820 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |