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| Product name: | PE/TR Anti-Human CD58 Antibody |
| Catalog: | DL23065F |
| Synonyms : | Lymphocyte function-associated antigen 3,CD58,Ag3,Surface glycoprotein LFA-3,LFA3 |
| Reactivity: | Human |
| Applications: | FCM |
| Size: | 20Tests |
| Host: | Mouse |
| Clonality: | |
| Background: | CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 965 |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |