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| Product name: | Anti-Human CD8a Monoclonal Antibody(PE Conjugated) |
| Catalog: | DL21338F |
| Synonyms : | T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL |
| Reactivity: | Human |
| Applications: | FCM |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests |
| Host: | Mouse |
| Clonality: | |
| Background: | CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the ??3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. |
| Concentration: | |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 925 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |