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| Product name: | Purified Anti-Human CD45RO Monoclonal Antibody |
| Catalog: | DL21717F |
| Synonyms : | |
| Reactivity: | Human |
| Applications: | FCM |
| Size: | 25 ug/100 ug |
| Host: | Mouse |
| Clonality: | |
| Background: | CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines. |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300 |
| Dilution: | |
| Gene ID(Human): | 5788 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |