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| Product name: | Purified Anti-Human CD40 Monoclonal Antibody |
| Catalog: | DL20556F |
| Synonyms : | Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5 |
| Reactivity: | Human |
| Applications: | FCM |
| Size: | 25 ug/100 ug |
| Host: | Mouse |
| Clonality: | |
| Background: | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
| Concentration: | 0.2 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300 |
| Dilution: | |
| Gene ID(Human): | 958 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |