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| Product name: | Anti-Mouse CD103 Monoclonal Antibody(FITC Conjugated) |
| Catalog: | DL21019F |
| Synonyms : | Integrin alpha-E,Itgae,Integrin alpha M290,CD103 |
| Reactivity: | Mouse |
| Applications: | FCM |
| Size: | 25 ug/50 ug/100 ug/200 ug |
| Host: | Rat |
| Clonality: | |
| Background: | CD103 is a type I transmembrane glycoprotein known as ??E integrin or Integrin ??IEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-?? stimulation. In association with integrin ??7, CD103 is expressed as ??E/??7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
| Concentration: | 0.5 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 16407 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |