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Product name: | Purified Anti-Human CD62L Monoclonal Antibody |
Catalog: | DL20700F |
Synonyms : | L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22 |
Reactivity: | Human |
Applications: | FCM,WB |
Size: | 25 ug/100 ug |
Host: | Mouse |
Clonality: | |
Background: | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of na?ve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
Concentration: | 0.2 mg/mL |
Immunogen: | |
Purification_Method: | |
Buffer: | PBS with 0.05% Proclin300 |
Dilution: | |
Gene ID(Human): | 6402 |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |