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| Product name: | Anti-Mouse TCR γ/δ Monoclonal Antibody(FITC Conjugated) |
| Catalog: | DL21569F |
| Synonyms : | TCR-??/??, ??/?? TCR |
| Reactivity: | Mouse |
| Applications: | FCM |
| Size: | 25 ug/50 ug/100 ug/200 ug |
| Host: | Armenian Hamster |
| Clonality: | |
| Background: | T cell receptor (TCR) is a heterodimer consisting of an ?? and a ?? chain (TCR ??/??) or a ?? and a ?? chain (TCR ??/??). TCR ??/?? belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR ??/?? associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most ??/?? T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR ??/?? have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that ??/?? T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-??/??-bearing T cells in vitro, and to deplete peripheral TCR-??/??-bearing T cells in vivo. |
| Concentration: | 0.5 mg/mL |
| Immunogen: | |
| Purification_Method: | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Dilution: | |
| Gene ID(Human): | 110,066,110,067 |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |